摘 要: 目的 对文献报道及本院收治的急性对硝基氯苯中毒病例进行分析研究,总结其临床特点,为修订职业性急性对硝基氯苯中毒诊断分级标准提供依据。方法 通过检索数据库及收集本院的病历资料,对数据进行统计分析。结果 本研究显示,急性对硝基氯苯中毒潜伏期多为数分钟至72小时,最长可达24天,临床表现主要为神经系统症状、紫绀和酱油色尿,伴网织红细胞升高、血红蛋白下降、高铁血红蛋白阳性、海因氏小体阳性等实验室指标异常,肝酶和尿常规异常者也较常见。结论 急性对硝基氯苯中毒主要靶器官是血液系统,亦可影响肝脏及泌尿系统;以高铁血红蛋白血症和急性血管内溶血为主要临床特点。建议将高铁血红蛋白血症、溶血性贫血及肝肾功损害程度作为急性对硝基氯苯中毒的主要诊断和分级依据。 |
关键词: 急性 对硝基氯苯 中毒 高铁血红蛋白血症 |
中图分类号: R135.1;O625.612
文献标识码:
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基金项目: |
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Analysis on pulmonary ventilation function of 96 sanitation workers |
Li Xian, Zhang Feng1in, Tang Wei
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The General Hospital of Jilin Chemical Group Company, Jilin 132022, China
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Abstract: Objective To collect and ana1yze the acute nitrochlorobenzene poisoning cases from our hospital and refer-ences,summarize their clinical characteristics, thereby provide some basis for revising the diagnostic criteria of occupational acutenitroch1orobenzenepoisoning.Methods Through the retrieva1 of database and co11ection of our hospital's medica1 records,the cases of acute nitroch1orobenzene poisoning were collected, then, ana1yzed all the data.ResuIts The results showed that the latent period of acute nitroch1orobenzene poisoning might be from few minutes to 72 hours: the main c1inical manifestations were nervous system symptom, cyanosis, soy sauce color urine with increased reticu1ocyte count, decreased hemog1obin level and positive examination resu1ts of methemog1obin and Heinz body, additiona11y, the liver enzymes and urinary routine resu1ts might be a1ways abnorma1.Conclusion The results suggested that the primary target organ of acute nitroch1orobenzene poisoning main1y are b1ood, 1iver and urinary system, methemog1obinemia and acute intravascu1ar hemo1ysis shou1d be the primary c1inica1 characteristics.Therefore, it shou1d be reasonab1e to propose that methemog1obinemia, hemo1ytic anemia, 1iver damage and kidney function damage shou1d be taken as the main evidences for the diagnosis and grading of acute nitroch1orobenzene poisoning. |
Keywords: acute 4-chloronitrobenzene poisoning methemoglobinemia |