摘 要: 职业噪声性听力损失是一种多因素疾病,近年来的报道认为其与遗传因素存在一定的相关性;同时,关于噪声暴露与高血压的关系研究越来越多,且高血压亦受一定的遗传因素影响,因此本文就近年来关于职业性噪声暴露与听力损失、高血压发生可能存在的共同机制,以及相关基因多态性研究作一概述。 |
关键词: 噪声 听力损失 高血压 基因多态性 |
中图分类号: R135.8
文献标识码:
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基金项目: 国家自然科学基金资助项目(81202179);广东省自然科学基金资助项目(S2012040006490) |
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A review on the effect of exposure to occupational noise on auditory system and hypertension |
Li Jia-hui, Tao Zhi-min , Wang Zhi
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Guangzhou Twelfth People’s Hospital affiliated to Guangzhou Medical University, 510620, China
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Abstract: Objective Occupational noise-induced hearing loss (ONHL) is a multifactor disease. In recent years, many studies reported the correlations between heredity and ONHL, and also more and more reports pointed out that there might be some connections between occupational noise exposure and hypertension. Hypertension was also affected by some genetic factors. This paper reviewed the common mechanisms that may exist in hearing loss and hypertension due to occupational noise exposure, and the related gene polymorphisms studied in recent years. |
Keywords: noise hearing loss hypertension gene polymorphism |