摘 要: 真核细胞生物受各种外源性刺激因素影响,细胞会表现出微核及染色体畸变等变异形式, 该变异的研究和应用在检测技术研发、疾病防控治疗等领域都得到不断完善。本文对该变异产生原理、变异检测方法、变异的应用等不同方面加以综述。 |
关键词: 真核细胞 微核 染色体畸变 影响因素 实验应用 |
中图分类号: A
文献标识码: R594
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基金项目: 河北省2018年度医学科学研究重点课题计划(编号:20181383) |
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General situation of detection techniques for micronucleus and chromosome aberration in eukaryotic cells |
ZHAO Jun-peng, WANG Yu-jun, LI Xin-ying, GAO Jing, Cai Chao, ZHANG Wei
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(Functional Unit of Tangshan Municipal Center for Disease Control and Prevention, Tangshan 063000, China)
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Abstract: Affected by various exogenous stimuli, eukaryotic cells might show plenty of abnormal forms such as micronucleus and chromosome aberration. The research and application of the mutations had been much improving in various fields such as detection technology, disease control, etc.. This paper will make a brief summarization on the principles, detection methods and application, etc. of the mutations. |
Keywords: eukaryotic cells micronucleus chromosome aberration impact factors experimental application |