摘 要: 三氯乙烯(trichloroethylene,TCE)职业暴露可导致严重的药疹样皮炎,常合并发热、皮损、肝肾损伤、浅表淋巴结肿大等临床表现。目前,职业性三氯乙烯药疹样皮炎(occupational medicamentosa-like dermatitis due to TCE,OMLDT)临床治疗多人单一的糖皮质激素为主,长期使用易出现各种并发症而导致病情恶化,增加死亡风险。本综述旨在探讨OMLDT可行的治疗方式,为改进治疗方法、提高患者生存率提供新的思路。 |
关键词: 三氯乙烯(TCE) 药疹样皮炎 治疗 |
中图分类号: R135.7
文献标识码: A
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基金项目: 安徽省自然科学基金(2008085Q11385);安徽医科大学早期接触科研训练计划(2019-ZQKY-50) |
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Treatment strategy for occupational dermatitis medicamentosa-like of trichloroethylene |
LIU Zhi-yuan,ZHANG Jia-xiang,ZHU Qi-xing
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Anhui Medical University,Hefei 230032,China
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Abstract: Occupational exposure to trichloroethylene may induce severe medicamentosa-like dermatitis,which is often associated with a series of clinical manifestations such as fever,skin lesions,liver and kidney injury,and superficial lymphadenopathy,etc.At present,most of the clinical treatment for this disease is single glucocorticoid therapy,but long-term hormone therapy will be easy to induce various complications and even lead to deterioration of the disease,thereby increase the risk of death.The purpose of this review is to discuss several feasible treatment strategies for occupational dermatitis medicamentosa-like of trichloroethylene,thereby provide some new ideas for the clinical treatment of the disease and improve patient survival. |
Keywords: trichloroethylene(TCE) medicamentosa-like dennatitis treatment |