摘 要: 毒蛇咬伤事件时有发生。在医疗欠发达地区判断被咬伤者的蛇毒种类大多是以临床症状和非特异的实验室血液检验结果为依据,但不同种属蛇毒引起的症状存在重叠或相似的情况,因此,准确性很低,给临床救治带来极大的困难。本文就近些年来国内外学者对于蛇毒素鉴别的常用检测方法,如色谱法、质谱法、紫外线检测法、聚合酶链式反应检测法以及免疫学测定法进行综述。 |
关键词: 蛇毒素 中毒 检测 |
中图分类号: R595.8
文献标识码: A
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基金项目: 广西医疗卫生适宜技术开发与推广应用项目(S2019098) |
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Rapid detection and its research progress of snake venom |
TAN Xing-ling,NING Zong
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Department of General Medicine,First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China
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Abstract: Snake bites occur frequently. In the areas with underdeveloped medical care,the identification of snakes mostly was based on clinical symptoms and non-specific laboratory blood examination. However,the symptoms caused by various snake venoms might be overlapping or similar,therefore,the accuracy was quite low,which also brought great difficulties to clinical treatment. The paper will make a brief review on some detect methods commonly used in recent years,such as chromatography,mass spectrometry,ultraviolet detection,polymerase chain reaction detection and immunological detection etc. |
Keywords: snake venom venenation detection |