| 摘 要: 黑索今（hexogen，RDX）为一种具有高度爆炸性的化合物，由于性能良好被广泛应用于军事和工业中，其带来的健康损害同时也越来越受到关注。本文现对近年来RDX的一般毒性、毒代动力学及神经毒性机制等研究资料进行汇总，为RDX神经毒性机制的深入研究奠定基础。 |
| 关键词: 黑索今（RDX） 毒代动力学 神经毒性 机制 |
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中图分类号: R994.3
文献标识码: A
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| 基金项目: |
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| Research progress on neurotoxicity of hexogen |
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GAO Ting，LIU Zhi-yong，GAO Yong-chao，LI Cun-zhi，ZHAO Bin，LI Huan，FAN Peng，GAO Jun-hong
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CNGC Institute of Industrial Health，Xi'an，710065，China
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| Abstract: Hexogen（RDX）is a highly explosive compound，which is widely used in military and industries due to its good performance.With the wide use of RDX，the health damage by it has also attracted more and more attention.In this paper，the general toxicity，toxicokinetics，neurotoxicity and its mechanism of RDX were summarized，thereby to lay a foundation for the fur ther study of the neurotoxicity mechanism of RDX. |
| Keywords: hexogen（RDX） toxicokinetics neurotoxicity |
