摘 要: 目的 研究日光温室作业对蔬菜种植人员脂代谢的影响。方法 采取整群抽样方法,选取西北某地区744名日光温室蔬菜种植人员(温室组)和231名非日光温室蔬菜种植人员(非温室组)作为研究对象;收集其一般人口学信息,并以血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDLC)、低密度脂蛋白胆固醇(LDLC)、TG/HDLC和LDLC/HDLC作为脂代谢的观测指标,比较温室组和非温室组人群脂代谢差异,分析引起脂代谢改变的可能危险因素。结果 温室组HDLC [(1.52±0.29)mmol/L] 低于非温室组 [(1.96±0.44)mmol/L],TG/HDLC(1.02±0.68)、LDLC/HDLC(1.85±0.94)均高于非温室组(0.76±0.50和1.43±1.14,P<0.05)。此外,温室组男性和女性HDLC [分别为(1.50±0.31)mmol/L、(1.54±0.01)mmol/L]均低于非温室组 [分别为(1.92±0.49)mmol/L、(1.97±0.03)mmol/L,P<0.05],TG/HDLC和LDLC/HDLC比值均高于非温室组(P<0.05)。多重线性回归分析表明,从事日光温室蔬菜种植作业和体质指数(BMI)对HDLC、TG/HDLC、LDLC/HDLC有影响。结论 血清HDLC、TG/HDLC和LDLC/HDLC改变与从事日光温室作业有关,可能作为监测日光温室蔬菜种植人员脂代谢异常的敏感指标。 |
关键词: 日光温室作业 脂代谢 高密度脂蛋白胆固醇(HDLC) |
中图分类号: R139.2
文献标识码: A
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基金项目: |
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Effect of greenhouse work on lipid metabolism of vegetable growers |
WANG Hong-fei,HE Wei,YAN Teng-long,YANG Si-wen,GAO Pan-jun,GU Yi-shuo,ZHU Xiao-jun,MA Wen-jun,LI Jue,LI Tao
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National Institute of Occupational Health and Poison Control,Chinese Center for Disease Control and Prevention,Beijing 100050,China
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Abstract: Objective To study the effect of greenhouse work on lipid metabolism of vegetable growers. Methods The cluster sampling method was used in the study, 744 vegetable greenhouse workers in northwest China were selected as greenhouse group and 231 common vegetable growers as control group. Their general demographic information were collected, the levels of serum total cholesterol (TC), triglycerides (TG), high density lipoprotein cholesterol (HDLC) and low density lipoprotein cholesterol (LDLC) were detected, thereby calculate the ratio of TG/HDLC and LDLC/HDLC, all of them were used as the indicators of lipid metabolism for comparing of the difference between greenhouse workers and common vegetable growers, and the risk factors were analyzed as well. Results The results showed that the HDLC level of greenhouse group [(1.52±0.29)mmol/L] was lower than that of control group [(1.96±0.44)mmol/L, P<0.05], while the ratios of TG/HDLC (1.02±0.68) and LDLC/HDLC (1.85±0.94) of greenhouse group were all higher than that of control group (0.76±0.50和1.43±1.14, respectively, P<0.05). The gender analysis showed that the average HDLC levels of both male workers [(1.50±0.31)mmol/L] and female workers [(1.54±0.01)mmol/L] were both lower than that of control group [(1.92±0.49)mmol/L and (1.97±0.03)mmol/L, P<0.05], and additionally, the ratios of TG/HDLC and LDLC/HDLC were also higher than that of control group (P<0.05). The multiple linear regression analysis showed that the greenhouse work and body mass index (BMI) were the risk factors of HDLC, TG/HDLC and LDLC/HDLC. Conclusion The results showed that serum HDLC, TG/HDLC and LDLC/HDLC were sensitive to lipid metabolism in greenhouse workers and related to BMI and greenhouse work, therefore, it is reasonable to use them as the surveillance indicator of lipid metabolism in greenhouse workers . |
Keywords: greenhouse work lipid metabolism high density lipoprotein cholesterol(HDLC) |